Suicide Aitempts among Patients Treated with Antidepressants, Mansoura Emergency Hospital, Toxicology Unit (2006--2009)

Document Type : Original Article


1 Department of Clinical Pharmacology, Faculty of Medicine, Mansoura University, Egypt

2 Department of Pathology, Faculty of Medicine, Mansoura University, Egypt


Suicide attempt includes any self-destructive behavior with the intension of ending one's /ife.ll may
or may not result in injuries. Intentional drug overdose is the most frequent method of suicide attempts
(parasuicide). Controversy regarding the issue of antidepressams contributing to suicidal behavior con
tinues in the literature. This work aims to (1) determine socio-demographic criteria of parasuicidal pa
tients on current antidepressam treatment presented to Mansoura Emergency Hospital- Toxicology Unit
with intentional drug overdose, and (2) highlight the use pattern of di.fferelll types of antidepressants and
their potential risk of suicidal attempts according to patient subgroups. It was found that the commonest
interuional drug overdose is the current antidepressant medication with high incidence rate for Tricyclic
antidepressants (TCA) followed by selective serotonin reuptake inhibitors (SSR/s). Female to Male ratio
was 1 S:J. Further research is essential to identify subpopulalions at risk of suicidal behavior to establish
preventive strategies agains1 recurrenJ altempts.